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Semaglutide works by: Reducing appetite by acting on receptors in the brain that control hunger and satiety Slowing gastric emptying , which helps you feel fuller for longer after meals Improving blood sugar regulation by enhancing insulin secretion when glucose levels are elevated Wegovy is administered as a once-weekly subcutaneous injection, typically starting at a low dose (0.25 mg) and gradually increasing over 16-20 weeks to the maintenance dose of 2.4 mg, as outlined in the Summary of Product Characteristics (SmPC)